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WEEK 6: Discussion Advanced PATHOPHYSIOLOGY Total Points Possible: 100 points Requirements: A 12-year-old boy is brought to the office for evaluation of hives. He has no significant past medical history and no history of allergies. He has just joined the middle school soccer team and noticed that he gets hives about 10 minutes into practice. The hives are itchy and consist of irregular blotches on his legs and trunk, about 10–20 cm in size, and they persist for about 30 minutes. He does not experience swelling of the lips or oropharynx and denies any wheezing or shortness of breath. His physical examination is normal without skin lesions or oral swelling at that moment, and his lungs are clear. After evaluation, he is diagnosed with urticaria. Discuss the likely cause of the patient’s urticaria. Describe the cellular mechanism of urticaria and how it leads to the signs and symptoms experienced by the patient. Describe the relationship between the patient’s symptoms and the concept of inflammation. What pharmacological and non-pharmacologic treatment options are available?  Discuss the complications of urticaria. What teaching would be appropriate to provide the parent and child about urticaria? Support your response with at least one current evidence based resource DISCUSSION CONTENT Category Points % Description Application of Course Knowledge 30 30% Posts make direct reference to concepts discussed in the lesson or drawn from relevant, evidence based outside sources, AND Posts are on topic and answer all presented questions which demonstrates a solid understanding of the topic. Applies concepts to personal experience in the professional setting and or relevant application to real life, AND Decisions are well supported with evidence-based arguments that are in-line with the scenario; AND Proper rationale and reasoning skills are demonstrated; AND Information is taken from source(s) with appropriate interpretation/evaluation to develop a comprehensive analysis or synthesis of the topic Support From Evidence Based Practice 30 30% Discussion post is supported with appropriate, scholarly sources; AND Sources are published within the last 5 years (unless it is the most current clinical practice guideline (CPG); AND Reference list is provided and in-text citations match; AND Provides relevant evidence of scholarly inquiry clearly stating how the evidence informed or changed professional or academic decisions Interactive Dialogue 30 30% Student provides a substantive* response to at least two topic-related posts of a peer; AND Evidence from appropriate scholarly sources are included; AND Reference list is provided and in-text citations match; AND Student responds to all direct faculty questions OR if student was not asked a direct question, student responds to either a 3rd peer post or a faculty question directed towards another student (*) A substantive post adds new content or insights to the discussion thread and information from student’s original post is not reused in peer or faculty response 90 90% Total CONTENT Points= 90 pts DISCUSSION FORMAT Category Points % Description Grammar, Syntax, Spelling, & Punctuation 10 10% Grammar, spelling, and/or punctuation are accurate, or with zero to one error. Direct quotes in discussions are limited to one short quotation (not to exceed 15 words). The quote adds substantively to the discussion.  (*) APA style references and in text citations are required; however, there are no deductions for errors in indentation or spacing of references. All elements of the reference otherwise must be included. 10 10% Total FORMAT Points= 10 pts DISCUSSION TOTAL=100 points

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